Title : Epicatechin gallate and epigallocatechin gallate are potent inhibitors of human arylacetamide deacetylase.

Pub. Date : 2021 Aug

PMID : 34171773






1 Functional Relationships(s)
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1 ECg and EGCg also strongly inhibited AADAC-mediated rifampicin hydrolase activity in human liver microsomes with IC50 values of 2.2 +- 1.4 and 1.7 +- 0.4 muM, respectively, whereas it weakly inhibited p-nitrophenyl acetate hydrolase activity, which is catalyzed by AADAC, CES1, and CES2. epigallocatechin gallate carboxylesterase 1 Homo sapiens