Title : Early serum albumin changes in patients with ulcerative colitis treated with tacrolimus will predict clinical outcome.

Pub. Date : 2021 Jun 14

PMID : 34168412






6 Functional Relationships(s)
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1 Early serum albumin changes in patients with ulcerative colitis treated with tacrolimus will predict clinical outcome. Tacrolimus albumin Homo sapiens
2 AIM: To examine serum albumin (Alb) level as a prognostic factor for the therapeutic effect of tacrolimus in clinical practice. Tacrolimus albumin Homo sapiens
3 AIM: To examine serum albumin (Alb) level as a prognostic factor for the therapeutic effect of tacrolimus in clinical practice. Tacrolimus albumin Homo sapiens
4 In the Kaplan-Meier analysis, a week 2/week 0 Alb ratio <= 1 had a significantly higher failure rate than that of > 1; Cox proportional hazard regression analysis also showed that a week 2/week 0 Alb ratio <= 1 was an independent prognostic factor for failure within 3 mo after the start of tacrolimus treatment. Tacrolimus albumin Homo sapiens
5 In the Kaplan-Meier analysis, a week 2/week 0 Alb ratio <= 1 had a significantly higher failure rate than that of > 1; Cox proportional hazard regression analysis also showed that a week 2/week 0 Alb ratio <= 1 was an independent prognostic factor for failure within 3 mo after the start of tacrolimus treatment. Tacrolimus albumin Homo sapiens
6 CONCLUSION: A week 2/week 0 Alb ratio <= 1 predicts failure within 3 mo of tacrolimus administration for UC. Tacrolimus albumin Homo sapiens