Title : PKA and AKIP1 interact to mediate cAMP-driven COX-2 expression: A potentially pivotal interaction in preterm and term labour.

Pub. Date : 2021

PMID : 34166397






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Here, we have extended these observations, using primary myometrial cell cultures to show that the cAMP agonist, forskolin, enhances IL-1beta-driven COX-2 expression. Colforsin cathelicidin antimicrobial peptide Homo sapiens
2 Forskolin alone and with IL-1beta increased IkappaBalpha mRNA expression suggesting that in the context of inflammation and in the presence of AKIP1, cAMP enhances p65 activation. Colforsin cathelicidin antimicrobial peptide Homo sapiens