Pub. Date : 2021 Sep
PMID : 34162690
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In our study, apically expressed breast cancer resistance protein (BCRP) and P-glycoprotein (P-gp) transported atorvastatin, fluvastatin, pitavastatin, and rosuvastatin. | Atorvastatin | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 2 | In our study, apically expressed breast cancer resistance protein (BCRP) and P-glycoprotein (P-gp) transported atorvastatin, fluvastatin, pitavastatin, and rosuvastatin. | Atorvastatin | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 3 | For atorvastatin, the corresponding values for P-gp-mediated efflux were 32-73% and 56%, respectively. | Atorvastatin | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 4 | These data indicate that BCRP may play an important role in limiting the intestinal absorption and facilitating the biliary excretion of rosuvastatin and that P-gp may restrict the intestinal absorption and mediate the biliary excretion of atorvastatin. | Atorvastatin | ATP binding cassette subfamily B member 1 | Homo sapiens |