Title : The protective effect of small peptides from Periplaneta americana on hydrogen peroxide-induced apoptosis of granular cells.

Pub. Date : 2021 Jun

PMID : 34155600






2 Functional Relationships(s)
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1 Moreover, the H2O2 treatment group showed significantly downregulated expression of SIRT1 (P < 0.01) but significantly upregulated expressions of p53 and Caspase3 (P < 0.01) compared to the control group. Hydrogen Peroxide tumor protein p53 Homo sapiens
2 This study suggests that SPPA inhibits H2O2-induced human KGN cell apoptosis through antioxidation, and the SIRT1/p53 signal pathway mediates the antioxidation. Hydrogen Peroxide tumor protein p53 Homo sapiens