Pub. Date : 2021
PMID : 34149998
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | SYVN1/GPX5 axis affects ischemia/reperfusion induced apoptosis of AC16 cells by regulating ROS generation. | Reactive Oxygen Species | synoviolin 1 | Homo sapiens |
2 | In I/R-induced AC16 cells, the expression of SYVN1 was up-regulated, and SYVN1 knock-down decreased the ROS levels and apoptotic rate but increased GPX5 levels. | Reactive Oxygen Species | synoviolin 1 | Homo sapiens |
3 | Moreover, GPX5 knockdown promoted ROS production and apoptosis, while its effects were attenuated by SYVN1 knockdown. | Reactive Oxygen Species | synoviolin 1 | Homo sapiens |