Title : SYVN1/GPX5 axis affects ischemia/reperfusion induced apoptosis of AC16 cells by regulating ROS generation.

Pub. Date : 2021

PMID : 34149998






3 Functional Relationships(s)
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1 SYVN1/GPX5 axis affects ischemia/reperfusion induced apoptosis of AC16 cells by regulating ROS generation. Reactive Oxygen Species synoviolin 1 Homo sapiens
2 In I/R-induced AC16 cells, the expression of SYVN1 was up-regulated, and SYVN1 knock-down decreased the ROS levels and apoptotic rate but increased GPX5 levels. Reactive Oxygen Species synoviolin 1 Homo sapiens
3 Moreover, GPX5 knockdown promoted ROS production and apoptosis, while its effects were attenuated by SYVN1 knockdown. Reactive Oxygen Species synoviolin 1 Homo sapiens