Title : Combined effects of low-dose gambogic acid and NaI131 in drug-resistant non-small cell lung cancer cells.

Pub. Date : 2021 Aug

PMID : 34149899






1 Functional Relationships(s)
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1 Compared with the PBS control group, the A549, A549/DDP and A549/Taxol cells treated with NaI131, GA or a combination of the drugs exhibited G2/M arrest and increased percentages of total apoptotic cells, as well as significantly decreased protein levels of CDK1, cyclin B, mtp53, HSP90, Bcl-2 and P-gp, increased protein levels of Bax and decreased mRNA levels of p53 and HSP90. gambogic acid tumor protein p53 Homo sapiens