Title : Structural basis for CSPG4 as a receptor for TcdB and a therapeutic target in Clostridioides difficile infection.

Pub. Date : 2021 Jun 18

PMID : 34145250






1 Functional Relationships(s)
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1 Two C. difficile exotoxins (TcdA and TcdB) are major virulence factors associated with these infections, and chondroitin sulfate proteoglycan 4 (CSPG4) is a potential receptor for TcdB, but its pathophysiological relevance and the molecular details that govern recognition remain unknown. Chondroitin Sulfates chondroitin sulfate proteoglycan 4 Mus musculus