Title : Phenolic Compounds of Red Wine Aglianico del Vulture Modulate the Functional Activity of Macrophages via Inhibition of NF-κB and the Citrate Pathway.

Pub. Date : 2021

PMID : 34122722






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 CIC, ACLY, and citrate are components of the citrate pathway: in LPS-activated macrophages, the mitochondrial citrate is exported by CIC into the cytosol where it is cleaved by ACLY in oxaloacetate and acetyl-CoA, precursors for ROS, NO , and PGE2 inflammatory mediators. Oxaloacetic Acid ATP citrate lyase Homo sapiens