Title : Central Regulation of PCOS: Abnormal Neuronal-Reproductive-Metabolic Circuits in PCOS Pathophysiology.

Pub. Date : 2021

PMID : 34122341






2 Functional Relationships(s)
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Protein Name
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1 Increased GnRH pulse frequency can promote LH secretion, leading to ovarian dysfunction and abnormal sex steroids synthesis. Steroids gonadotropin releasing hormone 1 Homo sapiens
2 By contrast, peripheral sex steroids can modulate the action of GnRH neurons through a feedback effect, which is impaired in PCOS, thus forming a vicious cycle. Steroids gonadotropin releasing hormone 1 Homo sapiens