Pub. Date : 2021 Sep
PMID : 34116393
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Magnesium treatment on methylation changes of transmembrane serine protease 2 (TMPRSS2). | Magnesium | transmembrane serine protease 2 | Homo sapiens |
| 2 | Magnesium treatment on methylation changes of transmembrane serine protease 2 (TMPRSS2). | Magnesium | transmembrane serine protease 2 | Homo sapiens |
| 3 | This study aims to test the hypothesis that magnesium (Mg) treatment leads to DNA methylation changes in TMPRSS2. | Magnesium | transmembrane serine protease 2 | Homo sapiens |
| 4 | This study aims to test the hypothesis that magnesium (Mg) treatment leads to DNA methylation changes in TMPRSS2. | Magnesium | transmembrane serine protease 2 | Homo sapiens |
| 5 | CONCLUSIONS: Among individuals ages < 65 y with calcium-to-magnesium intake ratios equal to or over 2.6, reducing the ratio to around 2.3 increased 5-methylcytosine modifications (i.e., cg16371860) and reduced 5-hydroxymethylcytosine modifications (i.e., cg26337277) in the TMPRSS2 gene. | Magnesium | transmembrane serine protease 2 | Homo sapiens |
| 6 | These findings, if confirmed, provide another mechanism for the role of Mg intervention in the prevention of COVID-19 and treatment of early and mild disease by modifying the phenotype of the TMPRSS2 genotype. | Magnesium | transmembrane serine protease 2 | Homo sapiens |