Title : Induction of monoamine oxidase A-mediated oxidative stress and impairment of NRF2-antioxidant defence response by polyphenol-rich fraction of Bergenia ligulata sensitizes prostate cancer cells in vitro and in vivo.

Pub. Date : 2021 Aug 20

PMID : 34097996






1 Functional Relationships(s)
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1 Notably, the differential inactivation of NRF2-antioxidant response pathway by PFBL resulted in death in PC3 versus NKE cells involving GSK-3beta activity facilitated by AKT inhibition. pfbl AKT serine/threonine kinase 1 Homo sapiens