Title : Phenotyping Angiotensin-Converting Enzyme in Blood: A Necessary Approach for Precision Medicine.

Pub. Date : 2021 Sep 1

PMID : 34097042






2 Functional Relationships(s)
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1 ACE phenotyping includes (a) determination of ACE activity with 2 substrates (Z-Phe-His-Leu (ZPHL) and Hip-His-Leu (HHL)), (b) calculation of a ratio for hydrolysis of ZPHL and HHL, and (c) quantification of ACE immunoreactive protein levels and ACE conformation with a set of monoclonal antibodies (mAbs) to ACE. hippuryl-histidyl-leucine angiotensin I converting enzyme Homo sapiens
2 ACE phenotyping includes (a) determination of ACE activity with 2 substrates (Z-Phe-His-Leu (ZPHL) and Hip-His-Leu (HHL)), (b) calculation of a ratio for hydrolysis of ZPHL and HHL, and (c) quantification of ACE immunoreactive protein levels and ACE conformation with a set of monoclonal antibodies (mAbs) to ACE. hippuryl-histidyl-leucine angiotensin I converting enzyme Homo sapiens