Pub. Date : 2021
PMID : 34078815
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Co-administration of panduratin A (50 mg/kg BW) orally improved kidney function and ameliorated renal tubule injury of cisplatin by inhibiting activation of extracellular signal-regulated kinase (ERK)1/2 and caspase 3. | Cisplatin | mitogen-activated protein kinase 3 | Homo sapiens |
2 | In human renal proximal tubular cells, cisplatin induced cell apoptosis by activating pro-apoptotic proteins (ERK1/2 and caspase 3), and reducing the anti-apoptotic protein (Bcl-2). | Cisplatin | mitogen-activated protein kinase 3 | Homo sapiens |