Pub. Date : 2022 Feb
PMID : 34078115
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | IL-6 inhibitors (sirukumab, tocilizumab, sarilumab) significantly enhance metabolism via CYP2C9 (s-warfarin), CYP2C19 (omeprazole), and CYP3A4 (simvastatin, midazolam) and reduce metabolism via CYP1A2 (caffeine). | Simvastatin | interleukin 6 | Homo sapiens |