Title : New nimesulide derivatives with amide/sulfonamide moieties: Selective COX-2 inhibition and antitumor effects.

Pub. Date : 2021 Oct 5

PMID : 34077833






2 Functional Relationships(s)
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1 New nimesulide derivatives with amide/sulfonamide moieties: Selective COX-2 inhibition and antitumor effects. nimesulide mitochondrially encoded cytochrome c oxidase II Homo sapiens
2 Experimental analyses showed that among seventeen compounds, N8 and N10 have remarkable potency and selectivity for the COX-2 enzyme over COX-1 at very low doses as compared to nimesulide. nimesulide mitochondrially encoded cytochrome c oxidase II Homo sapiens