Title : Anti-Inflammatory Effect of Auranofin on Palmitic Acid and LPS-Induced Inflammatory Response by Modulating TLR4 and NOX4-Mediated NF-κB Signaling Pathway in RAW264.7 Macrophages.

Pub. Date : 2021 May 31

PMID : 34072916






2 Functional Relationships(s)
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1 However, auranofin significantly inhibited the levels of NO, monocyte chemoattractant protein-1, and pro-inflammatory cytokines, such as interleukin (IL)-1beta, tumor necrosis factor-alpha, and IL-6, which had been increased by co-treatment with PA and LPS. Auranofin interleukin 1 alpha Homo sapiens
2 Moreover, the expression of inducible NO synthase, IL-1beta, and IL-6 mRNA and protein levels increased by PA and LPS were reduced by auranofin. Auranofin interleukin 1 alpha Homo sapiens