Title : Initiation of Pancreatic Cancer: The Interplay of Hyperglycemia and Macrophages Promotes the Acquisition of Malignancy-Associated Properties in Pancreatic Ductal Epithelial Cells.

Pub. Date : 2021 May 11

PMID : 34064969






2 Functional Relationships(s)
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1 Exposure to macrophages and elevated glucose levels (25 mM glucose) impacted gene expression of EMT inducers such as IL-6 and TNF-alpha as well as EMT transcription factors in benign (H6c7-pBp) and premalignant (H6c7-kras) PDEC. Glucose interleukin 6 Homo sapiens
2 Exposure to macrophages and elevated glucose levels (25 mM glucose) impacted gene expression of EMT inducers such as IL-6 and TNF-alpha as well as EMT transcription factors in benign (H6c7-pBp) and premalignant (H6c7-kras) PDEC. Glucose interleukin 6 Homo sapiens