Title : Jorunnamycin A Suppresses Stem-Like Phenotypes and Sensitizes Cisplatin-Induced Apoptosis in Cancer Stem-Like Cell-Enriched Spheroids of Human Lung Cancer Cells.

Pub. Date : 2021 May 3

PMID : 34063628






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Interestingly, pretreatment with jorunnamycin A at 0.5 muM for 24 h considerably sensitized lung CSCs to cisplatin-induced apoptosis, as evidenced by upregulated p53 and decreased Bcl-2 in jorunnamycin A-pretreated CSC-enriched spheroids. Cisplatin tumor protein p53 Homo sapiens