Title : Mitochondrial dysfunction as a driver of NLRP3 inflammasome activation and its modulation through mitophagy for potential therapeutics.

Pub. Date : 2021 Jul

PMID : 34022434






1 Functional Relationships(s)
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1 Mitochondrial dysfunction and subsequent accumulation of mitochondrial reactive oxygen species, mitochondrial deoxyribonucleic acid, and other mitochondria-associated proteins and lipids play vital roles in the instigation of the NLRP3 inflammasome. Reactive Oxygen Species NLR family pyrin domain containing 3 Homo sapiens