Title : Glucose and NAADP trigger elementary intracellular β-cell Ca2+ signals.

Pub. Date : 2021 May 21

PMID : 34021189






1 Functional Relationships(s)
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1 The consensus model, as well as a class of currently prescribed anti-diabetic drugs, are based around the observation that glucose-evoked ATP production in beta-cells leads to closure of cell membrane ATP-gated potassium (KATP) channels, plasma membrane depolarisation, Ca2+ influx, and finally the exocytosis of insulin granules. Adenosine Triphosphate insulin Homo sapiens