Title : ACE2 and SARS-CoV-2 Infection Risk: Insights From Patients With Two Rare Genetic Tubulopathies, Gitelman's and Bartter's Syndromes.

Pub. Date : 2021

PMID : 34017843






1 Functional Relationships(s)
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Protein Name
Organism
1 GS/BS patients" increased ACE2 and Ang 1-7 levels and their characteristic chronic metabolic alkalosis suggest a mechanism similar to that of chloroquine/hydroxychloroquine effect on ACE2 glycosylation alteration with resulting SARS-COV-2 binding inhibition and blockage/inhibition of viral entry. Hydroxychloroquine angiotensin converting enzyme 2 Homo sapiens