Title : The ERRĪ±-VDR axis promotes calcitriol degradation and estrogen signaling in breast cancer cells, while VDR-CYP24A1-ERRĪ± overexpression correlates with poor prognosis in patients with basal-like breast cancer.

Pub. Date : 2022 Feb

PMID : 34003583






1 Functional Relationships(s)
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1 Vitamin D is used to reduce cancer risk and improve the outcome of cancer patients, but the vitamin D receptor (VDR; also known as the calcitriol receptor) pathway needs to be functionally intact to ensure the biological effects of circulating calcitriol, the active form of vitamin D. Vitamin D vitamin D receptor Homo sapiens