Title : LKB1-PTEN axis controls Th1 and Th17 cell differentiation via regulating mTORC1.

Pub. Date : 2021 Aug

PMID : 34003330






1 Functional Relationships(s)
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1 Mechanistically, LKB1 directly binds and phosphorylates phosphatase and tensin homolog (PTEN), an upstream regulator of mammalian target of rapamycin complex 1 (mTORC1), which is independent of AMP-activated protein kinase (AMPK). Sirolimus phosphatase and tensin homolog Homo sapiens