Pub. Date : 2021 Oct
PMID : 33999329
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Isorhamnetin Alleviates High Glucose-Aggravated Inflammatory Response and Apoptosis in Oxygen-Glucose Deprivation and Reoxygenation-Induced HT22 Hippocampal Neurons Through Akt/SIRT1/Nrf2/HO-1 Signaling Pathway. | 3-methylquercetin | thymoma viral proto-oncogene 1 | Mus musculus |
| 2 | Isorhamnetin alleviated the HG-aggravated OGD/R injury in HT22 cells through Akt/SIRT1/Nrf2/HO-1 signaling pathway. | 3-methylquercetin | thymoma viral proto-oncogene 1 | Mus musculus |
| 3 | Meanwhile, treatment with Akt inhibitor LY294002 reversed the protective effects of isorhamnetin against HG-aggravated OGD/R injury in HT22 cells. | 3-methylquercetin | thymoma viral proto-oncogene 1 | Mus musculus |
| 4 | In a conclusion, Isorhamnetin alleviates HG-aggravated OGD/R in HT22 hippocampal neurons through Akt/SIRT1/Nrf2/HO-1 signaling pathway. | 3-methylquercetin | thymoma viral proto-oncogene 1 | Mus musculus |