Pub. Date : 2021 May
PMID : 33997184
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Tetrandrine inhibits proliferation of colon cancer cells by BMP9/ PTEN/ PI3K/AKT signaling. | tetrandrine | phosphatase and tensin homolog | Homo sapiens |
| 2 | Furthermore, we demonstrated that Tet reduces phosphorylated PTEN, which can be promoted by overexpressed BMP9, analogously also be attenuated through silencing BMP9. | tetrandrine | phosphatase and tensin homolog | Homo sapiens |
| 3 | Our findings suggested that the anti-cancer activity of Tet in SW620 cells may be mediated partly by up-regulating BMP9, followed by inactivation PI3K/Akt through up-regulating PTEN at least. | tetrandrine | phosphatase and tensin homolog | Homo sapiens |