Pub. Date : 2021
PMID : 33995632
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Lenvatinib induces anticancer activity in gallbladder cancer by targeting AKT. | lenvatinib | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | Treatment with lenvatinib decreased the expression of MMP-2, CEMIP, CDK2, CDK4 and cyclin D1, and increased the expression of cleaved caspase-9, which was mediated by the inactivation of the PI3K/AKT pathway in vitro. | lenvatinib | AKT serine/threonine kinase 1 | Homo sapiens |
| 3 | Besides, Lenvatinib suppressed GBC cell growth in vivo by targeting p-AKT. | lenvatinib | AKT serine/threonine kinase 1 | Homo sapiens |