Title : Stimulation of α7 Nicotinic Acetylcholine Receptor by Nicotine Suppresses Decidual M1 Macrophage Polarization Against Inflammation in Lipopolysaccharide-Induced Preeclampsia-Like Mouse Model.

Pub. Date : 2021

PMID : 33995360






2 Functional Relationships(s)
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1 Then, we further investigated the regulatory role of alpha7nAChR activation by nicotine on decidual macrophage polarization and placental remodeling in the PE-like mouse model. Nicotine cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus
2 alpha-bungarotoxin (alpha-BGT) which is specific antagonist for alpha7nAChR could abolish the effects of nicotine on decidual macrophage polarization, trophoblast arrangement and vascular structure in placental tissue in PE mice. Nicotine cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus