Title : Dihydrotanshinone Inhibits Hepatocellular Carcinoma by Suppressing the JAK2/STAT3 Pathway.

Pub. Date : 2021

PMID : 33995073






4 Functional Relationships(s)
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1 Immunofluorescence results have showed that DHTS decreased STAT3 nuclear translocation. dhts signal transducer and activator of transcription 3 Homo sapiens
2 Moreover, Western blot results have demonstrated that DHTS suppressed the activation of JAK2/STAT3 signaling pathway. dhts signal transducer and activator of transcription 3 Homo sapiens
3 In addition, xenograft results have showed that DHTS suppressed tumor growth of SMMC7721 cells in vivo by inhibiting the p-STAT3. dhts signal transducer and activator of transcription 3 Homo sapiens
4 Thus, we demonstrated that DHTS could inhibit HCC by suppressing the JAK2/STAT3 pathway. dhts signal transducer and activator of transcription 3 Homo sapiens