Pub. Date : 2021
PMID : 33995046
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In addition, CYP1A2 inactivation by individual furanocoumarin bioactive was concentration- and time-dependent involving the irreversible inhibition mechanism. | Furocoumarins | cytochrome P450 family 1 subfamily A member 2 | Homo sapiens |
| 2 | Thus, furanocoumarin bioactive metabolism in humans would result in reactive metabolite(s) formation inactivating CYP1A2 isozyme and inhibiting caffeine metabolism. | Furocoumarins | cytochrome P450 family 1 subfamily A member 2 | Homo sapiens |