Pub. Date : 2021
PMID : 33994848
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Upregulation of ATP Binding Cassette Subfamily C Member 5 facilitates Prostate Cancer progression and Enzalutamide resistance via the CDK1-mediated AR Ser81 Phosphorylation Pathway. | enzalutamide | ATP binding cassette subfamily C member 5 | Homo sapiens |
2 | The ABCC5-CDK1-AR regulatory pathway could be a potential therapeutic target for advanced prostate cancer, especially castration-resistant prostate cancer (CRPC), to enhance the therapeutic effect of enzalutamide. | enzalutamide | ATP binding cassette subfamily C member 5 | Homo sapiens |