Title : Cyclosporin A impairs neurogenesis and cognitive abilities in brain development via the IFN-γ-Shh-BDNF pathway.

Pub. Date : 2021 Jul

PMID : 33993101






5 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Cyclosporin A impairs neurogenesis and cognitive abilities in brain development via the IFN-gamma-Shh-BDNF pathway. Cyclosporine sonic hedgehog signaling molecule Homo sapiens
2 Here, we found that the immunosuppressant cyclosporin A (CsA) decreased the number of BrdU+, BrdU+/DCX+, BrdU+/NeuN + cells in the hippocampus, impaired learning and memory and inhibited protein levels of the shh signaling pathway, including Shh, Smo and Gli1. Cyclosporine sonic hedgehog signaling molecule Homo sapiens
3 Here, we found that the immunosuppressant cyclosporin A (CsA) decreased the number of BrdU+, BrdU+/DCX+, BrdU+/NeuN + cells in the hippocampus, impaired learning and memory and inhibited protein levels of the shh signaling pathway, including Shh, Smo and Gli1. Cyclosporine sonic hedgehog signaling molecule Homo sapiens
4 Here, we found that the immunosuppressant cyclosporin A (CsA) decreased the number of BrdU+, BrdU+/DCX+, BrdU+/NeuN + cells in the hippocampus, impaired learning and memory and inhibited protein levels of the shh signaling pathway, including Shh, Smo and Gli1. Cyclosporine sonic hedgehog signaling molecule Homo sapiens
5 Here, we found that the immunosuppressant cyclosporin A (CsA) decreased the number of BrdU+, BrdU+/DCX+, BrdU+/NeuN + cells in the hippocampus, impaired learning and memory and inhibited protein levels of the shh signaling pathway, including Shh, Smo and Gli1. Cyclosporine sonic hedgehog signaling molecule Homo sapiens