Title : A strategy to discover selective α-glucosidase/acetylcholinesterase inhibitors from five function-similar citrus herbs through LC-Q-TOF-MS, bioassay and virtual screening.

Pub. Date : 2021 Jun 1

PMID : 33992880






1 Functional Relationships(s)
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1 Interestingly, the different types of components in the herbs exhibited selectivity for different targets: flavanone glycosides are effective on alpha-glucosidase but ineffective on acetylcholinesterase; polymethoxyflavonoids are effective on acetylcholinesterase but ineffective on alpha-glucosidase. flavanone glycosides acetylcholinesterase (Cartwright blood group) Homo sapiens