Title : Multiple Computational Approaches for Predicting Drug Interactions with Human Equilibrative Nucleoside Transporter 1.

Pub. Date : 2021 Jul

PMID : 33980604






2 Functional Relationships(s)
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1 Mizoribine and ribavirin mapped to the ENT1 substrate pharmacophore and proved to be substrates of the ENTs. Ribavirin solute carrier family 29 member 1 (Augustine blood group) Homo sapiens
2 NBMPR also decreased ribavirin accumulation in ENT1 and ENT2 cells (ENT1: ~50% decrease p = 0.0498; ENT2: ~30% decrease p = 0.0125). Ribavirin solute carrier family 29 member 1 (Augustine blood group) Homo sapiens