Pub. Date : 2021 Jul
PMID : 33976430
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Here we show that retinoic acid-inducible gene-I (RIG-I) sufficiently restrains SARS-CoV-2 replication in human lung cells in a type I/III interferon (IFN)-independent manner. | Tretinoin | DExD/H-box helicase 58 | Homo sapiens |
| 2 | By contrast, the anti-SARS-CoV-2 activity was restored by all-trans retinoic acid treatment through upregulation of RIG-I protein expression in primary lung cells derived from patients with chronic obstructive pulmonary disease. | Tretinoin | DExD/H-box helicase 58 | Homo sapiens |