Title : Mucosal acidosis elicits a unique molecular signature in epithelia and intestinal tissue mediated by GPR31-induced CREB phosphorylation.

Pub. Date : 2021 May 18

PMID : 33972436






1 Functional Relationships(s)
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1 Utilizing loss- and gain-of-function approaches in cultured epithelia and murine colonoids, we demonstrate that EA elicits prominent CREB phosphorylation through cyclic AMP-independent mechanisms that requires elements of the mitogen-activated protein kinase signaling pathway. Cyclic AMP cAMP responsive element binding protein 1 Mus musculus