Title : Growth hormone replacement may influence the biological action of thyroid hormone on liver and bone tissue.

Pub. Date : 2021 Apr-Jun

PMID : 33971491






6 Functional Relationships(s)
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Protein Name
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1 OBJECTIVE: Growth hormone (GH) replacement alters the peripheral interconversion of thyroxine (T4) and triiodothyronine (T3). Triiodothyronine growth hormone 1 Homo sapiens
2 OBJECTIVE: Growth hormone (GH) replacement alters the peripheral interconversion of thyroxine (T4) and triiodothyronine (T3). Triiodothyronine growth hormone 1 Homo sapiens
3 OBJECTIVE: Growth hormone (GH) replacement alters the peripheral interconversion of thyroxine (T4) and triiodothyronine (T3). Triiodothyronine growth hormone 1 Homo sapiens
4 OBJECTIVE: Growth hormone (GH) replacement alters the peripheral interconversion of thyroxine (T4) and triiodothyronine (T3). Triiodothyronine growth hormone 1 Homo sapiens
5 RESULTS: GH replacement provoked a decline in serum free T4 concentration (-1.09 +- 1.99 pmol/L; p = 0.02) and an increase in free T3 (+0.34 +- 0.15 pmol/L; p = 0.03); therefore, the free T3:free T4 ratio increased from 0.40 +- 0.02 to 0.47 +- 0.02 (p = 0.002). Triiodothyronine growth hormone 1 Homo sapiens
6 RESULTS: GH replacement provoked a decline in serum free T4 concentration (-1.09 +- 1.99 pmol/L; p = 0.02) and an increase in free T3 (+0.34 +- 0.15 pmol/L; p = 0.03); therefore, the free T3:free T4 ratio increased from 0.40 +- 0.02 to 0.47 +- 0.02 (p = 0.002). Triiodothyronine growth hormone 1 Homo sapiens