Title : Hypoxic acclimation improves cardiac redox homeostasis and protects heart against ischemia-reperfusion injury through upregulation of O-GlcNAcylation.

Pub. Date : 2021 Jul

PMID : 33964586






1 Functional Relationships(s)
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1 Hyperglycosylation activated glucose-6-phosphate dehydrogenase (G6PDH), the rate-limiting enzyme in the pentose phosphate pathway, resulting in an upregulation of NADPH/NADP+ and GSH/GSSG couples and enhancement of redox homeostasis in the heart. NADP 2,4-dienoyl CoA reductase 1, mitochondrial Mus musculus