Title : Older-onset levodopa-responsive parkinsonism with normal DAT-SPECT and pterin hypometabolism.

Pub. Date : 2021 May 7

PMID : 33962918






1 Functional Relationships(s)
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1 GTP cyclohydrolase 1 (GCH-1) deficiency, which triggers pteridine hypometabolism and normally develops in childhood, can mediate an adult-onset decrease in levodopa production and dopa-responsive dystonia (DRD), with normal dopamine transporter single-photon emission computed tomography (DAT-SPECT). Levodopa solute carrier family 6 member 3 Homo sapiens