Title : Isoalantolactone Increases the Sensitivity of Prostate Cancer Cells to Cisplatin Treatment by Inducing Oxidative Stress.

Pub. Date : 2021

PMID : 33959604






2 Functional Relationships(s)
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1 Mechanistically, the combined treatment resulted in an excessive accumulation of intracellular reactive oxygen species (ROS), which leads to the activation of endoplasmic reticulum (ER) stress and the JNK signaling pathway in human prostate cancer cells. Reactive Oxygen Species mitogen-activated protein kinase 8 Homo sapiens
2 Mechanistically, the combined treatment resulted in an excessive accumulation of intracellular reactive oxygen species (ROS), which leads to the activation of endoplasmic reticulum (ER) stress and the JNK signaling pathway in human prostate cancer cells. Reactive Oxygen Species mitogen-activated protein kinase 8 Homo sapiens