Title : Molecular docking-guided synthesis of NSAID-glucosamine bioconjugates and their evaluation as COX-1/COX-2 inhibitors with potentially reduced gastric toxicity.

Pub. Date : 2021 Jul

PMID : 33955172






2 Functional Relationships(s)
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1 Molecular docking-guided synthesis of NSAID-glucosamine bioconjugates and their evaluation as COX-1/COX-2 inhibitors with potentially reduced gastric toxicity. Glucosamine mitochondrially encoded cytochrome c oxidase II Homo sapiens
2 Furthermore, in an intriguing result, we observed that the mefenamic-acid-glucosamine bioconjugate displayed enhanced activity towards COX-1 rather than COX-2. Glucosamine mitochondrially encoded cytochrome c oxidase II Homo sapiens