Title : Nicotine Enhances Firing Activity of Layer 5 Pyramidal Neurons in the Medial Prefrontal Cortex through Inhibition of Kv7 Channels.

Pub. Date : 2021

PMID : 33952828






2 Functional Relationships(s)
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1 The effect of nicotine was blocked by the alpha4beta2 nicotinic acetylcholine receptor (nAChR) antagonist dihydro-beta-erythroidine, alpha7 nAChR antagonist methyllycaconitine, or intracellular perfusion with the Ca2+ chelator 1,2-bis(2-aminophenoxy)ethane-N,N,N",N"-tetraacetic acid (BAPTA). Nicotine cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus
2 The effect of nicotine was blocked by the alpha4beta2 nicotinic acetylcholine receptor (nAChR) antagonist dihydro-beta-erythroidine, alpha7 nAChR antagonist methyllycaconitine, or intracellular perfusion with the Ca2+ chelator 1,2-bis(2-aminophenoxy)ethane-N,N,N",N"-tetraacetic acid (BAPTA). Nicotine cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus