Pub. Date : 2021 Jun 9
PMID : 33952632
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In this study, we tested the hypothesis that tacrolimus, a calcineurin inhibitor, prevents age-associated microstructural atrophy, which we measured using higher-order diffusion MRI, in the middle-aged beagle brain (n = 30, male and female). | Tacrolimus | calcineurin binding protein 1 | Homo sapiens |
| 2 | In this study, we show that administration of the calcineurin inhibitor, tacrolimus, over one year prevents age and AD-associated microstructural changes in the hippocampus, parahippocampal cortex, and prefrontal cortex of the middle-aged beagle brain, with no noticeable adverse effects. | Tacrolimus | calcineurin binding protein 1 | Homo sapiens |