Title : Receptor-mediated mitophagy regulates EPO production and protects against renal anemia.

Pub. Date : 2021 May 4

PMID : 33942716






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Mechanistically, EPO production is impaired in REPs in Fundc1-/- mice upon stresses, and the impairment is caused by the accumulation of damaged mitochondria, which consequently leads to the elevation of the reactive oxygen species (ROS) level and triggers inflammatory responses by up-regulating proinflammatory cytokines. Reactive Oxygen Species erythropoietin Mus musculus
2 Mechanistically, EPO production is impaired in REPs in Fundc1-/- mice upon stresses, and the impairment is caused by the accumulation of damaged mitochondria, which consequently leads to the elevation of the reactive oxygen species (ROS) level and triggers inflammatory responses by up-regulating proinflammatory cytokines. Reactive Oxygen Species erythropoietin Mus musculus