Title : TRIM25 activates AKT/mTOR by inhibiting PTEN via K63-linked polyubiquitination in non-small cell lung cancer.

Pub. Date : 2022 Mar

PMID : 33931764






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 This modification prevents the plasma membrane translocation of PTEN and reduces its phosphatase activity therefore accumulating PI(3,4,5)P3. phosphoinositide-3,4,5-triphosphate phosphatase and tensin homolog Homo sapiens