Title : Striatin genotype-based, mineralocorticoid receptor antagonist-driven clinical trial: study rationale and design.

Pub. Date : 2021 Jun 1

PMID : 33904521






1 Functional Relationships(s)
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1 It is designed to determine if participants with the STRN risk alleles will have a greater BP reduction on a liberal salt diet with a specific, mechanism-based therapy - a mineralocorticoid receptor antagonist, eplerenone - as compared with a nonspecific anti-hypertensive therapy - amlodipine. Eplerenone nuclear receptor subfamily 3 group C member 2 Homo sapiens