Title : MYBL2 disrupts the Hippo-YAP pathway and confers castration resistance and metastatic potential in prostate cancer.

Pub. Date : 2021

PMID : 33897882






1 Functional Relationships(s)
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1 Importantly, targeting MYBL2, or treatment with either the YAP/TAZ inhibitor Verteporfin or the RhoA inhibitor Simvastatin, reversed the resistance to ADT and blocked bone metastasis in CRPC cells. Simvastatin ras homolog family member A Homo sapiens