Title : G-Protein-coupled Estrogen Receptor 1 Agonist G-1 Perturbs Sunitinib Resistance-related Phosphoproteomic Signatures in Renal Cell Carcinoma.

Pub. Date : 2021 May-Jun

PMID : 33893075






1 Functional Relationships(s)
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1 Phosphoproteomic signatures, including phosphoinositide 3-kinase and protein kinase B (PI3K-AKT) as well as other pathways, were up-regulated in sunitinib-resistant cells but application of G-1 reversed this effect. Sunitinib AKT serine/threonine kinase 1 Homo sapiens