Title : G-Protein-coupled Estrogen Receptor 1 Agonist G-1 Perturbs Sunitinib Resistance-related Phosphoproteomic Signatures in Renal Cell Carcinoma.

Pub. Date : 2021 May-Jun

PMID : 33893075






2 Functional Relationships(s)
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1 MATERIALS AND METHODS: Parental and sunitinib-resistant 786-O cells were treated with GPER1 agonist G-1, and quantitative phosphoproteomics was performed. Sunitinib G protein-coupled estrogen receptor 1 Homo sapiens
2 CONCLUSION: Our results open up the possibility for managing RCC and sunitinib resistance by GPER1 agonist G-1 and its regulated pathways. Sunitinib G protein-coupled estrogen receptor 1 Homo sapiens