Title : Kinetic and toxicological effects of synthesized palladium(II) complex on snake venom (Bungarus sindanus) acetylcholinesterase.

Pub. Date : 2021

PMID : 33889183






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The enzyme AChE provokes the hydrolysis of substrate acetylcholine (ACh) in the nervous system and terminates nerve impulse. Acetylcholine acetylcholinesterase (Cartwright blood group) Homo sapiens
2 Results: Statistical analysis showed that krait venom AChE inhibition decreases with the increase of Pd(II) complex (0.025-0.05 microM) and exerted 61% inhibition against the AChE at a fixed concentration (0.5 mM) of ACh. Acetylcholine acetylcholinesterase (Cartwright blood group) Homo sapiens
3 It was observed that K m (Michaelis-Menten constant of AChE-ACh into AChE and product) increased from 0.108 to 0.310 mM (45.74 to 318.35%) and V max remained constant with an increase of Pd(II) complex concentrations. Acetylcholine acetylcholinesterase (Cartwright blood group) Homo sapiens